Using MOFA for integration of omics data

omics
live training

Using MOFA for integration of omics data

Target Audience:
All VIB staff
Location:

Leuven

General context

This training provides an introduction to Multi-Omics Factor Analysis (MOFA) for the integration of different omic data sets in an unsupervised fashion. It will enable you to run MOFA on multi-omic data, identify and explore the major drivers of variations across omics and use the inferred factors in various downstream analyses.

Approach
  • What kind of preprocessing of the data is required for MOFA?
  • How to train MOFA on a multi-omic data set?
  • How to interpret the MOFA factors by their loadings, using gene set enrichment or sample ordination?
  • How to use MOFA for downstream analyses including regression, classification or clustering?
  • How to impute missing values with MOFA?
  • How to select the number of factors and compare different MOFA fits?
Required skills

Familiarity with R and RStudio.

Software demonstrated

MOFA (Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets) - http://msb.embopress.org/content/14/6/e8124

Trainers

Ricard Argelaguet

Research Scientist, Altos Labs UK.

Program

-

TBC

Practical info

Location & Venue
Leuven - Park Inn by Radisson

Martelarenlaan 36
3010 Leuven
Belgium

Public transport
Leuven - Park Inn by Radisson
Public transport

The hotel is located 300m from Leuven Central Station. The hotel connects to Leuven Central Station by a pedestrian bridge.

Route description
Leuven - Park Inn by Radisson
Parking

Park Inn hotel has no own parking. It is possible to park underground in P1-Parking Station Leuven, Martelarenlaan 4, 3010 Leuven or in parking De Bond, Martelarenlaan 18, 3010 Leuven.

Venue contact
Leuven - Park Inn by Radisson
Location contact

+32 16 61 66 02

sales.leuven@parkinn.com

Extra information
  • This course is free for VIB participants
  • Registration fee for non-VIB academics is 50 Euro.
  • Registration fee for non-VIB academics is 300 Euro.
  • Note that upon no show without valid justification you will be blacklisted for the VIB training program for 1 year. Click here for more information.