Genome Engineering
Genome Engineering
1 day course
General context
Genome engineering technologies – with CRISPR/Cas undoubtedly being the most important one – have evolved rapidly in recent years. To keep up to date with new tools, applications and developments, we organize a VIB training day on ‘Genome Engineering’.
The aim of this training day is – after a brief introduction – to highlight new, more advanced CRISPR- applications. The training focusses specifically on the practical implementation of the technology in the lab, through experts sharing their know-how concerning CRISPR applications. Topics will include Cas9 fusions that enhance editing efficiency and precision and enable new types of genome control, such as DNA methylation. We will end with a keynote highlighting practical applications of the CRISPR technology.
Poster session:
Participants will also have the opportunity to discuss their work with experts in the field during a competitive poster session (poster award of 150 €). You can submit your abstract for the poster session using the form below before 4 November 2019. Presenting a poster is not obligatory, but please note that we will give priority to who has submitted an abstract for the poster sessions if there is a waiting list.
This training targets scientists who want to keep up-to-date with the latest evolutions in the field of genome editing. There will be a brief introduction on the basics of CRISPR, but the focus will be on advanced CRISPR applications. The training is aimed at PhD students, postdoctoral fellows, technicians or other scientists with a molecular biology background.
Thomas Jacobs (VIB-UGent Center for Plant Systems Biology)
Sven Eyckerman (VIB-UGent Center for Medical Biotechnology)
Marlies Vanden Bempt (VIB-KULeuven Center for Cancer Biology)
- Participation is free for VIB participants.
- Registration fee for Academics from Universities and Centers of Excellence is € 50 per day (21% VAT incl.).
- Registration fee for participants of EU-LIFE partner institutes is € 50 per day (21% VAT incl.).
- Registration fee for industry is € 300 per day (21% VAT incl.).
- Note that upon no-show without valid justification you will be blacklisted for the VIB training program for 1 year and for VIB participants the reimbursement of the catering costs (€ 50) will be charged to the research group. Click here for more information.
- If you would like to present a poster, please submit your abstract below. Please note that uploading your abstract does not mean that you are subscribed for the training. To register, you need to click the button 'Register for this course' in the top left corner.
Trainers
Luca Crepaldi
Toon Swings
Tony Gutschner
Florian Veillet
Javier Gallego-Bartolomé
Dirk Daelemans
Program
Introduction
Analysis and prediction of CRISPR-Cas9 mutational outcomes at scale
Luca Crepaldi, Wellcome Sanger Institute, Hinxton, UK
Off-the-shelf genome engineering in E. coli
Toon Swings, VIB-KU Leuven Center for Microbiology, BE
Coffee
Deaminases and knock-in
Enhancing homology-dependent repair in human cells using Cas9 fusion proteins
Tony Gutschner, Faculty of Medicine, Martin Luther University Halle-Wittenberg MLU, DE
Base editing in plants : successes, limits and new tools
Florian Veillet, Institut de Génétique Environnement et Protection des Plantes (IGEPP), INRA, Université Rennes, FR
Lunch
Poster session
Poster session
Coffee
CRISPR/Cas9 in vivo dependency mapping reveals EZH2 as druggable target in desmoid tumors
Thomas Naert, Department of Biomedical Molecular Biology, Ghent University, Cancer Research Institute Ghent, BE – selected form the abstracts
CRISPRi
Targeted manipulation of DNA methylation in plants
Keynote
CRISPR-based genetic screening tools for cancer drug discovery
Dirk Daelemans, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, BE
Award for best poster
Drink with the speakers (optional)
Practical info
Leuven - Provinciehuis Vlaams-Brabant
Provincieplein 1
3010 Leuven
Belgium
Leuven - Provinciehuis Vlaams-Brabant
Provinciehuis Vlaams-Brabant is located within walking distance of the Leuven railway and bus station. When exiting the station, go left across the Roger Van Overstraetenplein.
Leuven - Provinciehuis Vlaams-Brabant
There is a dedicated cycling path next to the Leuven ring road where you can ride in both directions. You can park your bike right next to or underneath the building. Using your bike for longer distances? Check out Cycle Highways?
Leuven - Provinciehuis Vlaams-Brabant
From the E40, take the E314 and immediately exit at junction 15 towards Leuven city center. Follow the road to the Leuven ring road, turn right towards Tienen and Diest, and continue past the Tiense Poort. As you approach the Provinciehuis, stay in the right lane and continue towards the station until the end. Then, carefully turn right and drive slowly, respecting pedestrians and cyclists, under the pedestrian bridge (Roger Van Overstraetenplein) until you reach the railway. Turn right and follow the tracks towards Provinciehuis.
Park on Bezoekersparking floor -2.
Using GPS? Older GPS software may not recognize 'Provincieplein' as an address. In that case, enter 'Tiensevest - intersection with Justus Lipsiusstraat' instead.
Leuven - Provinciehuis Vlaams-Brabant
+32 16 26 70 15
provinciehuis@vlaamsbrabant.be