Using MOFA for integration of omics data

Using MOFA for integration of omics data

omics
Location:

Leuven

Start date:

03 May 2019

Duration:
03 May 2019

General context

This training provides an introduction to Multi-Omics Factor Analysis (MOFA) for the integration of different omic data sets in an unsupervised fashion. It will enable you to run MOFA on multi-omic data, identify and explore the major drivers of variations across omics and use the inferred factors in various downstream analyses.

Approach
  • What kind of preprocessing of the data is required for MOFA?
  • How to train MOFA on a multi-omic data set?
  • How to interpret the MOFA factors by their loadings, using gene set enrichment or sample ordination?
  • How to use MOFA for downstream analyses including regression, classification or clustering?
  • How to impute missing values with MOFA?
  • How to select the number of factors and compare different MOFA fits?
Required skills

Familiarity with R and RStudio.

Software demonstrated

MOFA (Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets) - http://msb.embopress.org/content/14/6/e8124

Trainers

Ricard Argelaguet

Predoctoral Fellow in the Stegle  and Marioni research group of the European Bioinformatics Institute

Program

-

TBC

Practical info

Location & Venue
Park Inn by Radisson Leuven

Martelarenlaan 36
3010 Leuven
Belgium

Public transport
Park Inn by Radisson Leuven
Public transport

The hotel is located 300m from Leuven Central Station. The hotel connects to Leuven Central Station by a pedestrian bridge.

Route description
Park Inn by Radisson Leuven
Parking

Park Inn hotel has no own parking. It is possible to park underground in P1-Parking Station Leuven, Martelarenlaan 4, 3010 Leuven.

Venue contact
Park Inn by Radisson Leuven
Location contact

+32 16 61 66 02

sales.leuven@parkinn.com

Extra information
  • This course is free for VIB participants
  • Registration fee for non-VIB academics is 50 Euro.
  • Registration fee for non-VIB academics is 300 Euro.
  • Note that upon no show without valid justification you will be blacklisted for the VIB training program for 1 year. Click here for more information.