Organoid modelling of human development and disease: where we stand and where we go to
Organoid modelling of human development and disease: where we stand and where we go to
General context
Organoids have the potential to revolutionize the in vitro modelling of tissue morphogenesis and organogenesis, regenerative medicine and tissue engineering, drug discovery process and disease modelling. The goal of this symposium is to enhance our understanding of how organoids can be generated and maintained and how they can be used to study disease.
The symposium will start with an general introduction on advantages and limitations of the use of organoids, requirements for the technique and comparison with other (in vivo and in vitro) models. A next session will focus on organoid modelling of human development, especially on endoderm and neural development. Further more, we will also address organoids in disease modelling and therapeutic (or pharmacological) intervention.
Leading researchers in the field will update the participants on the most recent innovations, concerns as well as practical challenges encountered and solutions proposed in the fields of organoids. In addition, junior researchers of the invited labs will present a more hands-on approach on the topics, to make the discussions more lively and down-to-earth.
As one of the goals of this symposium is to bring together leading academic scientists with more junior researchers to exchange and share their experiences and research results on all aspects of organoid modelling, we will give the participants the possibility to book a seat at the table with the speakers during the coffee breaks and lunch. Also, we will end the day with a round table discussion with the speakers.
This training targets scientists who want to learn about the latest developments in organoid modelling of human development and disease. It is aimed at PhD students, postdoctoral fellows, technicians or other scientists with a molecular biology background.
- Gabriele Bergers (VIB-KU Leuven Center for Cancer Biology)
- Max Mazzone (VIB-KU Leuven Center for Cancer Biology)
- Pierre Vanderhaeghen (VIB-KU Leuven Center for Brain & Disease Research)
- Participation is free for VIB participants.
- Registration fee for Academics from Universities and Research Centers is € 50 (21% VAT incl.).
- Registration fee for participants of EU-LIFE partner institutes is € 50 (21% VAT incl.).
- Registration fee for industry is € 300 (21% VAT incl.).
- Note that upon no-show without valid justification you will be blacklisted for the VIB training program for 1 year and for VIB participants the reimbursement of the catering costs (€ 50) will be charged to the research group. Click here for more information.
Trainers
Arnold Kriegstein
Madeline Andrews
Matthias Lutolf
Jakob Langer
Henner Farin
Mohammed Mosa
Emile Voest
Vivien Veninga
Silvia Cappello
Francesco Di Matteo
Bon-Kyoung Koo
Amanda Andersson Rolf
Program
Welcome
Benchmarking cerebral organoids against the human brain
Arnold Kriegstein, Department of Neurology and Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, US
Madeline Andrews, School of Biological and Health Systems Engineering, Arizona State University, US
Engineering epithelial organoid development
Matthias Lutolf & Jakob Langer, Institute of Bioengineering, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, CH - online talk
Coffee break (possibility to book a seat at the table with the speakers)
Organoid-stroma biobank for modeling the tumor microenvironment and therapy responses in colorectal cancer
Henner Farin & Mohammed Mosa, Georg Speyer Haus, Institute for Tumor Biology and Experimental Therapy, DE
Lunch (possibility to book a seat at the table with the speakers)
Tumor organoids: key in research, clinical decision making or both?
Emile Voest & Vivien Veninga, Medical Oncology, Netherlands Cancer Institute, NL
Extracellular Signaling in Neurodevelopmental Disorders
Silvia Cappello & Francesco Di Matteo, Max Planck Institute of Psychiatry, DE
Coffee break (possibility to book a seat at the table with the speakers)
CRISPR/Cas-assisted genetics in intestinal organoids
Bon-Kyoung Koo, Center for Genome Engineering, IBS, KR
Round table discussion with all speakers
Practical info
25 May 2022
Leuven - Provinciehuis Vlaams-Brabant
Provincieplein 1
3010 Leuven
Belgium
25 May 2022
Leuven - Provinciehuis Vlaams-Brabant
Provinciehuis Vlaams-Brabant is located within walking distance of the Leuven railway and bus station. When exiting the station, go left across the Roger Van Overstraetenplein.
25 May 2022
Leuven - Provinciehuis Vlaams-Brabant
There is a dedicated cycling path next to the Leuven ring road where you can ride in both directions. You can park your bike right next to or underneath the building. Using your bike for longer distances? Check out Cycle Highways?
25 May 2022
Leuven - Provinciehuis Vlaams-Brabant
From the E40, take the E314 and immediately exit at junction 15 towards Leuven city center. Follow the road to the Leuven ring road, turn right towards Tienen and Diest, and continue past the Tiense Poort. As you approach the Provinciehuis, stay in the right lane and continue towards the station until the end. Then, carefully turn right and drive slowly, respecting pedestrians and cyclists, under the pedestrian bridge (Roger Van Overstraetenplein) until you reach the railway. Turn right and follow the tracks towards Provinciehuis.
Park on Bezoekersparking floor -2.
Using GPS? Older GPS software may not recognize 'Provincieplein' as an address. In that case, enter 'Tiensevest - intersection with Justus Lipsiusstraat' instead.
25 May 2022
Leuven - Provinciehuis Vlaams-Brabant
+32 16 26 70 15
provinciehuis@vlaamsbrabant.be